Wrinkle creams are popular over the counter products found in your local pharmacy or drugstore designed to help fight off premature aging, restore youth, as well as preventing future damage or wrinkles.
The compounds found inside many popular wrinkle creams have anti-inflammatory, antioxidative, and protective effects on the skin, with some studies even narrowing in on possible anti-cancer and wrinkle reduction properties.
Best Wrinkle Cream
1Neutrogena Rapid Wrinkle Repair Moisturizer with Sunscreen
This rapid anti-aging wrinkle cream includes hyaluronic acid and SPF 30 sunscreen to protect your face and keep you moisturized and free of any wrinkles. Neutrogena Rapid Wrinkle Repair has been clinically tested and shown too visibly reduce the appearance of wrinkles and fine lines, including crow’s feet and forehead. The Retinol works continuously throughout the day, working to renew skin and reduce age spots and discoloration. The glucose complex accelerates the activity on the surface of your skin to achieve rapid results.
The hyaluronic acid can hold up to 1,000 times its weight in water, so it quenches dry skin and offers incredible moisture while remaining lightweight and absorbing quickly without clogging pores. Meanwhile, the SPF 30 sunscreen offers protection from UVA and UVB rays, allowing you to enjoy your time in the sun without worrying about aging your skin.
Simply apply it twice a day to your face and neck. Massage it gently into your skin until it is fully absorbed. It is gentle enough to be used every day and safe for all skin tones.
2Kleem Organics Advanced Retinol Moisturizer Age Defying Solution
This product is a best seller in its category, and for good reason. Kleem Organics Advanced Retinol Moisturizer is vegan and contains no parabens, phthalates, mineral oils, or synthetic fragrances. It is also gluten-free and does not use animal testing, so you can rest assured that no cruelty was involved in creating it. It is free of alcohol and non-acnegenic and non-comedogenic, so it is suitable for all skin types, even sensitive skin.
This anti-aging face cream uses retinol along with hyaluronic acid, vitamin C, vitamin E, green tea, and jojoba for a deep hydration that lasts for up to 72 hours. It will help your skin produce collagen and elastin, reducing the appearance of crow’s feet, wrinkles, and fine lines. It even boosts your skin’s ability to retain moisture.
Kleem Organics Advanced Retinol Moisturizer uses 5 proven bio-active ingredients (Retinol, hyaluronic acid, vitamin E, green tea, and jojoba oil) that will enhance your skin without leaving residue or toxins behind.I t will also increase the elasticity of your skin, making it even more firm and reducing sags and bags. The anti-aging vitamins will smooth over and even out your skin’s texture, making sure that your complexion is radiant and has a youthful glow. Kleem Organics Advanced Retinol Moisturizer was manufactured in the USA in a facility that was approved by the FDA and endorsed by PETA as certified cruelty-free.
3InstaNatural Vitamin C Moisturizer
InstaNatural Vitamin C Moisturizer uses aloe vera, niacinamide, hyaluronic acid, and sunflower seed oil to correct wrinkles and hyperpigmentation. It’s suitable for men and women.The serum is made with no parabens, no mineral oil, no SLS or SLES, no formaldehyde or ingredients that release formaldehyde, no petroleum, no polyethylene glycol (PEGs), no DEA, MEA, or TEA, and no unsafe preservatives. InstaNatural Vitamin C Moisturizer is made in the USA using materials and never tested on animals.
This moisturizer uses vitamin C for a youthful glow to your skin. It contains several high quality ingredients that offer a massive boost of antioxidants to benefit your skin. Vitamin C increases the production of collagen and reduces the appearance of wrinkles, dark spots, and fine lines.
The formula is very lightweight, packed with the best ingredients for major hydration without the oil and grease. These include niacinamide, hyaluronic acid, organic jojoba, rosehip seed oil, argan oil, and grapefruit extract. This ingredient list clears dry patches and flakes off your skin. The moisturizer brightens your dull skin, reduces signs of aging, and evens your skin tone. This offers smooth and supple looking skin by boosting natural production. You can layer it with cleansers, toners, and serums for a full skincare routine.
4LilyAna Naturals Retinol Cream Moisturizer
The LilyAna Naturals cream uses an advanced formula to combat aging that can be used daily and nightly. The maximum strength formula doesn’t cause the skin to peel or flake and won’t dry out your face.
It is packed with organic ingredients like hyaluronic acid, vitamin E, green tea, shea butter, and jojoba oil. Men and women of all skin types can use it. The results are visible, with reductions in wrinkles and fine lines. LilyAna Naturals cream even fades the damage of sunspots, acne, and scars.
This formula will also improve uneven skin tones, creating a smooth overall texture and evening and brightening skin. It can repair and restore your skin, offering rejuvenation and life. It doesn’t leave oil behind, either. The LilyAna Naturals cream absorbs well and doesn’t feel sticky or weigh you down. It’s gentle and can be sued even around sensitive eyes to reduce bags and puffiness. It also contains no artificial fragrances or parabens and is gluten-free and cruelty-free.
5L’Oreal Paris Collagen Moisture Filler for Day and Night
L’Oreal Paris Collagen Moisture Filler For Day And Night provides your skin with intense hydration that will fill in all the wrinkles and fine lines and restore your skin to a plump, moist and glowing complexion. It is lightweight and does not leave grease on your skin It provides deep hydration and moisturizes any skin type.The formula even works overnight. The rapid results will let your skin feel smooth after just 1 week and within 1 month, it will fill in fine lines and wrinkles.
Collagen production and moisture diminish as you age, causing the skin to sag and be less plump and bouncy. The L’Oreal Paris Collagen Moisture Filler will restore your skin’s moisture and bounce, nourishing it and helping to boost collagen production. This reduces lines and wrinkles, offering glowing and radiant skin. It is non-comedogenic and has been tested for safety by dermatologists.
6Baebody Beauty Retinol Ultimate Moisturizer Cream
Baebody Beauty Retinol Ultimate Moisturizer Cream combines retinol with shea butter, vitamin E, vitamin B5, jojoba oil, and green tea to fight the appearance of fine lines and wrinkles while moisturizing your face. It is made in the USA and is never tested in animals.
Baebody Beauty Retinol Ultimate Moisturizer Cream is also safe for all skin types and free of phthalates and parabens. The retinol will remove fine lines and wrinkles while combating hyperpigmentation and other discoloration. Vitamin A will boost your skin’s natural renewal processes, which will remove the old and dull skin cells and replace them with new cells that offer a smooth and radiant appearance.
This is the second part of their 3 step skin routine. The glycolic acid cleanser goes first, exfoliating. This moisturizes and smooths your skin, transforming it. Finally, the eye gel enhances your eyes, reducing puffiness.
7Tree of Life Age Defying Beauty Retinol Serum for Face and Skin
The Tree of Life Age Defying Beauty Retinol Serum for Face and Skin is made in the USA. It is cruelty-free and never tested on animals. It also comes with a money back guarantee because the company stands behind its products. It is 72% organic and safe for all skin types.
This formula is clinical strength. Tree of Life Age Defying Beauty Retinol Serum for Face and Skin offers a smooth and refreshed skin tone as soon as it gets used, countering the adverse effects of aging skin and providing a youthful glow on soft skin. The anti-wrinkle serum creates vibrant and glowing skin tones. The retinol used boosts natural collagen production, creating youthful looking skin. The hyaluronic acid adds tons of moisture to the skin, without feeling greasy.
The The Tree of Life Age Defying Beauty Retinol Serum for Face and Skin is 98% natural and 72% organic. It is soft and moisturizes while targeting fine lines and age spots. It’s smooth and luxurious, made in regularly inspected facilities.
8Medix Retinol + Ferulic Acid Anti Sagging Treatment
The Medix Retinol + Ferulic Acid Anti Sagging Treatment, treats wrinkles with black tea, aloe vera, and chamomile. It is vegan, never tested on animals, free of parabens, alcohol free, and contains no PEGs, formaldehyde, sulfates, dyes, triclosan, propylene glycol, mineral oil, or talc.
Medix Retinol + Ferulic Acid Anti Sagging Treatment uses vitamin A and natural ferulic acid to decrease fine lines and wrinkles and target sun damage on your skin. The powerful antioxidants will rejuvenate your skin and return a youthful glow. Chamomile and the Botanimoist AMS will increase your skin’s hydration by up to 88% while smoothing away wrinkles and removing puffiness.
Additional natural ingredients, like aloe vera and black tea, improve your skin’s overall health and appearance. The shea butter, aloe vera, apple, sunflower, and rosemary will all work together to moisturize and hydrate your skin, leaving it feeling smooth.
9Cosmedica Skincare Pure Hyaluronic Acid Serum
The Cosmedica Skincare Pure Hyaluronic Acid Serum is made from the purest form of hyaluronic acid, offering intense moisture treatment for your skin to guard against aging and wrinkles. This serum is free of any parabens and offers a professional grade formula that is free of any grease and oil. It improves your skin’s texture, brightening it with extra moisture and balancing your skin tone. The 100% pure hyaluronic acid will offer deep moisture.
Cosmedica Skincare Pure Hyaluronic Acid Serum has been proven to reduce the signs of aging. It will diminish fine lines and wrinkles, removing forehead, cheek, and crow’s feet wrinkles and boosting your skin’s youthful glow. It is shown to offer plumper, softer skin with a smooth touch and texture.
Cosmedica products are created using the purest ingredients possible with the most advanced market innovations. This means that you have the best products that money can buy. Despite that, they insist on affordable products. This product is vegan and free of any cruelty. This serum can also reduce other signs of aging. It will diminish blemishes and reduce hyperpigmentation and dark spots.
10Eucerin Q10 Anti-Wrinkle Face Cream
Eucerin Q10 Anti-Wrinkle Face Cream offers moisture for a smooth, wrinkle-free skin tone. The product is fragrance free, alcohol free, and non-comedogenic, using vitamin E and beta-carotene to enrich the skin’s natural beauty.
Q10 is a coenzyme that occurs naturally inside your body. It defends your skin against the process of aging. The older you get, the lower your Q10 content becomes, so this moisturizer includes Q10 to replenish your body’s supply and help defend against wrinkles and signs of aging.
The Eucerin Q10 Anti-Wrinkle Face Cream multiple natural ingredients combine to protect your skin against the damage that free radicals cause. It also offers antioxidants that can help your skin rejuvenate itself and begin to naturally produce collagen and reduce wrinkles.
How We Rank
The first thing we looked at, when formulating our rankings for the best wrinkle creams, was third party testing, purity and clinical trials. All our products, like Kleem Organics and Baebody Beauty are manufactured in the USA, where standards are more rigorous. This means that all of these products are safe for consumption.
We next looked at the ingredients. We preferred active ingredients that were clinically tested, as to guarantee their effectiveness. Retinol has been studied extensively, and is the active ingredient in some of our top ranked products, like Neutrogena Rapid Wrinkle Repair. Another part of analyzing ingredients is ensuring they are all-natural. Most products on our list are vegan and are organic. This means that you won’t be putting parabens and toxins in your system.
Finally, we made sure that these products were cruelty free. Ethics in skincare is very important. Products that made our rankings, like LilyAna Naturals and Cosmedica, are never tested on animals. They are made from global ingredients that are ethically sourced through sustainable means.
After all this, we determined the top 10 best wrinkle creams on the market.
1Vitamin A acts as a powerful antioxidant, protecting the skin from free radicals; ultimately, preventing skin damage or wrinkles. Retinol is found on many wrinkle cream ingredient lists. It’s essentially composed of Vitamin A which is where it reaps its benefits from.
A 2007 study sought out to evaluate the benefits and effectiveness of topical retinol on already naturally aged skin. 36 elderly participants with an average age of 87 years old were involved in the study. The lotion used contained 0.4% retinol. It was applied 3 times a week to each participant for 24 weeks.
Skin biopsies were used as the main mode for measurement and evaluation. The results showed a substantial difference and improvement in fine wrinkle scores for the treated skin. Researchers concluded that this was likely due to water retention as well as increased collagen production. In fact, they also inferred that with a greater skin matrix, the skin was able to withstand damage or injury in the future (1).
Another study published in Cancer Epidemiology Biomarkers and Prevention even showed retinol to aid in reducing certain incidences of skin cancer – again, preventing damage to the skin and its structure. Researchers concluded that retinol could potentially aid in preventing squamous cell carcinoma. However, they also reported that it was not effective in preventing and reducing the risk of basal cell carcinoma (2).
A 2009 study published in the Journal of Dermatology further evaluated the effectiveness of retinol when it comes to reducing wrinkles and preventing them. 30 Japanese women with wrinkles in the corners of their eyes participated in this specific study. The lotion containing retinol was applied to one side of their face for 8 weeks. The retinol lotion showed to moderately improve wrinkles in 34% of subjects. Researchers also noted that it was well-tolerated and no participant experienced significant adverse effects (3).
Another study in the Journal of Investigative Dermatology Symposium Proceedings also observed retinol use in aging or damaged skin. The study found that retinol caused growth of keratinocytes and fibroblasts, as well as strengthened the extracellular matrix of the skin, demonstrating its protective effects (4).
2Vitamin C acts as an antioxidant and is known for preventing sun damage to the skin. A common ingredient, Vitamin C, in wrinkle cream products provides another protective compound. In a study published in the British Journal of Dermatology, researchers explored Vitamin C and its effect on sun-damaged skin.
The study showed that Vitamin C levels actually become depleted with sun exposure. This leaves the skin susceptible to damage. Researchers suggested that Vitamin C supplementation or topical application may prevent this damage from occurring (5).
A 2003 study observed the use of Vitamin C and E in UV photo-protection. The solution containing these two vitamins was applied to pig skin daily for 4 days straight. Researchers discovered that this application yielded antioxidative protective properties and effects. It was then suggested that these two vitamins be used to protect the skin from the sun and prevent skin cancer, as well as photoaging (6).
Another study supported the use of topical Vitamin C for skin protection. In this particular study, researchers observed Vitamin C and its effectiveness in skin protection via oral supplementation. But it was found that this type of administration had no real effect on oxidative stress in the skin (7).
3Hydroxy acids act as an exfoliant, removing dead skin cells, as well as stimulating the growth of new skin cells. Thus, they are thought to help improve the appearance of aged skin in this way, and various studies support this theory. A study in the Journal of the American Academy of Dermatology looked at the use of hydroxy acids in improving photoaged skin.
Participants applied a lotion for 6 months that contained 25% glycolic, lactic, or citric acid. The results showed a surprising 25% increase in skin thickness, improved elastic fiber quality, and increased collagen. Conclusively, researchers determined that hydroxy acids did improve photoaging (8).
Another study also evaluated the use of hydroxy acids in treating photodamaged skin. 74 women participated in the study, aging from 40-70 years of age. Each participant had moderate to severely photodamaged skin. The study concluded by saying that topical 8% glycolic acid and 8% L-lactic acid creams were somewhat useful when it came to treating photodamaged skin. These researchers also noted that such creams were tolerated well by the study’s participants (9).
In yet another study, skin peels involving hydroxy were examined in conjunction with an improvement in photoaged skin. These results showed mild improvements in the skin of the 44 participants. These improvements included decreased roughness, reduced fine wrinkles, and epidermal thickening (10).
4Coenzyme Q10 is often included in wrinkle cream products to reduce fine wrinkles around the eyes, as well as protect the skin from UV light damage. It is thought coenzyme Q10 does this via antioxidant properties as demonstrated in specific studies outlined below (11). One scientific article described coenzyme Q10 and its effects on the skin.
The authors determined that topical application of this specific ingredient improves mitochondrial function in the skin; thus improving overall skin health (12).
In one study narrowed in on coenzyme Q10 and its antioxidant effects. Researchers investigated coenzyme Q10 in topical applications and its role in preventing photoaging. It was found coenzyme Q10 reduced oxidation and wrinkle depth. Ultimately, it showed that coenzyme Q10 could prevent photoaging (13).
Another 2009 study also demonstrated similar effects and results. Researchers examined coenzyme Q10 in human dermal and epidermal cells. The results showed that coenzyme Q10 had protective effects involving preventing cell death and preventing oxidative stress (14).
5Peptides are another ingredient used in some wrinkle cream products to promote wound healing, reduce stretch marks, and prevent wrinkles. Peptides have growth factors that promote proper and effective healing of a wound on the skin. They have been used in a variety of ways to speed up the healing process and enhance it (15).
A 2015 review in the Journal of the European Academy of Dermatology and Venereology observed the use of topically applied peptide-containing lotion on stretch marks. Yet, the review failed to demonstrate solid evidence and studies solidifying the use of peptides in reducing stretch marks. In fact, the authors went on to say that further research is necessary to determine the efficacy of it (16).
Yet, another study showed peptides could potentially prevent and reduce wrinkles. 20 participants took part in the study. The topical lotion was applied around the eye area 2 times a day for 4 weeks. It was found that wrinkles were significantly reduced, including the number of wrinkles and their depth (17).
5Tea extracts can sometimes be found in wrinkle cream products which further the antioxidant effects of the product. In a 2013 study published in the Journal of Cosmetic Dermatology, researchers explored the use of green tea extract in preventing wrinkles. The lotion was applied for 8 weeks to the participants’ crow feet around their eyes.
Most participants reported moderate improvement in their wrinkles, giving way to researchers inferring that green tea extract does have antioxidant activity that can aid in preventing and reducing wrinkles (18).
Green tea extract was also observed for the use of reducing and improving photodamage. This particular study was conducted on mice. It was found that the lotion containing green tea extract was more effective in protecting the skin from UVB photodamage when compared to the control group (19).
6Grape seed extract promotes antioxidant effects, anti-inflammatory effects, and wound healing. One study even showed that grape seed extract was numerous times more effective than the commonly used Vitamin E (20).
1Retinol may cause redness, dryness, irritation, sensitivity to sunlight, redness, other skin discoloration, crusting, swelling, or blistering. It is always best when trying out a new product to try a small dime-sized amount on your wrist or forearm before applying it to your entire facial area (21).
2Hydroxy acids may cause similar reactions as retinol. Proceed with similar precautions. If you already have sensitive skin, hydroxy acids may cause increased irritation and aggravation.
3Coenzyme Q10 may cause some people to break out in allergic rashes. It is also cautioned to discontinue use of coenzyme Q10 at least 2 weeks before surgery.
4As with anything when pregnant, make sure to check with your doctor that it is safe to apply certain products and their ingredients to your skin.
There is no standard dosage for wrinkle creams as every product is different and every skin is slightly different.
For the FDA approved drug tretinoin, apply a pea-sized amount topically to the skin where wrinkles appear, using enough to lightly cover the entire affected area.
Do creams really help wrinkles? They can and they can’t. The effectiveness of anti-wrinkle creams depends in part on the active ingredient or ingredients.
What age should you start using anti-wrinkle cream? One can say, that from the age of 25-30 you should start to give your skin the protection it needs. UV filters and adapted anti-aging ingredients, such as creatine and hyaluronic acid, are therefore essential. Skin type and age play an important role in choosing the best face cream.
Does lemon juice help wrinkles? Yes, lemon juice can help wrinkles. Rid your face of dead skin cells by making a lemon juice mixture and applying it daily. The acid in the lemon juice will help to tighten up your skin, which can help eliminate the wrinkles that are caused by age.
Are anti-aging creams safe? Anti-aging products typically contain hydroxy acids to increase the permeability of the skin and allow anti-aging ingredients to pass through. For the most part, dermatologists hold that good skincare habits are a safe and effective alternative to investing in anti-aging creams.
Does coconut oil help with wrinkles? Coconut oil is an excellent massage oil for your skin and may be used as an effective moisturizer for all skin types. It may be massaged into the skin each night before bed to help reduce the appearance of fine lines and wrinkles and to reduce premature aging.
Does Preparation H work on wrinkles? Preparation H has long been known as an effective treatment for those who suffer from painful hemorrhoids, but it also has a more unusual use in some skin care circles, as some have found that using Preparation H for wrinkles works to lessen the appearances of eye bags and other fine lines and wrinkles around the eyes.
Does coconut oil get rid of wrinkles? Yes, coconut oil can help get rid of wrinkles. It may be massaged into the skin each night before bed to help reduce the appearance of fine lines and wrinkles and to reduce premature aging. There’s some evidence that coconut oil may help treat dermatitis better than other oils.
Is there a cure for wrinkles? The only FDA-approved topical treatment for wrinkles is tretinoin, known commercially as Retin A. Ashinoff says this prescription cream reduces fine lines and large wrinkles, and repairs sun damage.
What foods slow down aging? The best foods for slowing down aging are high in antioxidants. This includes foods such as olive oil, yogurt, dark chocolate, nuts, berries, fish and red wine.
Does apple cider vinegar help wrinkles? Yes, the vinegar acts as a toner; keeping skin cells hydrated which prevents wrinkles as well.
What is the best treatment for deep wrinkles? Retinoids are your best option when combatting deep wrinkles. Derived from vitamin A, retinoids — such as tretinoin (Renova, Retin-A) and tazarotene (Avage, Tazorac) — that you apply to your skin may reduce fine wrinkles, splotches, and skin roughness.
What home remedy can I use to look younger? Mix 2 tbsp pure coffee powder sans chicory with 2 tbsp unsweetened cocoa powder, 1 tsp honey, and a few drops each of milk and coconut oil to prepare a paste. Apply this on your face and wash off after 20 minutes to reveal an energized, younger looking skin. Use lemon juice in place of honey if your skin is oily.
What is the best treatment for face wrinkles? Treatments available for skin wrinkles include topical medical treatments (such as vitamin A acid, alpha hydroxy acids, antioxidants, and moisturizer) and more invasive procedures (such as glycolic acids peels, deep peels, dermabrasion, laser resurfacing, surgical procedures, injection of fillers, and Botox).
Are wrinkles permanent? Wrinkles are a natural part of the aging process. As people get older, their skin gets thinner, drier, less elastic, and less able to protect itself from damage. This leads to wrinkles, creases, and lines on the skin. Environmental factors such as smoking can accelerate the development of wrinkles.
Does coconut oil tighten skin? It has become a familiar staple in many kitchens and can also be used to tighten your skin. Coconut oil is a powerful antioxidant that works to eliminate free radicals that can damage your skin. In addition, coconut oil hydrates and moisturizes your skin, which prevents sagging.
Will wrinkle creams work the same as a face lift? Wrinkle cream won’t have the same effect as botox or a facelift. But these products can help improve the vitality, health, and look of your skin. They further may prevent future damage caused by age and sun exposure.
Wrinkle cream has become very popular in today’s society as individuals seek out solutions to aging or damaged skin. Commonly used ingredients in wrinkle cream products include retinol, Vitamin C, coenzyme Q10, hydroxy acids, peptides, tea extracts, and grape seed extract. These products aim to reduce and prevent wrinkles, encourage antioxidant effects and anti-inflammatory effects, promote wound healing, and more.
More specifically, retinol protects the skin from free radicals via antioxidant properties. In fact, it was even found in studies to reduce one’s risk of cancer, particularly squamous cell carcinoma. It was also found in scientific research to strengthen the extracellular matrix of the skin.
Vitamin C is commonly used in wrinkle creams primarily for its antioxidative effects. It’s well-known and scientifically proven to prevent skin damage caused by the sun and other means.
Hydroxy acids, on the other hand, are thought to help once the damage has been done by stimulating new growth of skin cells and getting rid of old skin cells. In a way, researchers believe this particular ingredient may act as an exfoliator of sorts.
Coenzyme Q10 is yet another antioxidant source, protecting the skin from damage and ultimately preserving it. It was even shown in one study to reduce wrinkle depth.
Peptides are another ingredient popular in wrinkle cream products. Although, further research would help solidify claims made based on peptides as an ingredient.
Tea extracts and grape seed extracts further had antioxidative effects, reducing the damage done by free radicals to the skin tissue.
Many of these ingredients were also well tolerated by participants throughout various studies, with few adverse side effects. Side effects primarily occur in those with sensitive skin or pre-existing conditions.
As aforementioned, when trying out a new product, make sure to first apply the wrinkle cream to the skin of your forearm or wrist and leave it for a few hours. If not adverse effects or irritation occurs, it is likely safe to apply to the face or other areas of the body.